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PCTK1 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q00536
Clone Names 6030452
Peptide ID 6030452
Additional Information
Gene ID 5127
Other Names Cyclin-dependent kinase 16, Cell division protein kinase 16, PCTAIRE-motif protein kinase 1, Serine/threonine-protein kinase PCTAIRE-1, CDK16, PCTAIRE1, PCTK1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDK16
Synonyms PCTAIRE1, PCTK1
Function Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser- 336' (in vitro).
Cellular Location Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse, synaptosome Note=Colocalizes with insulin in pancreas islets. Recruited to the cell membrane by CCNY
Tissue Location Detected in pancreas islets (at protein level). Detected in brain and pancreas
Research Areas
Citations (0)

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The protein encoded by this gene belongs to the cdc2/cdkxsubfamily of the ser/thr family of protein kinases. It may play arole in signal transduction cascades in terminally differentiatedcells; in exocytosis; and in transport of secretory cargo from theendoplasmic reticulum. This gene is thought to escape Xinactivation. Alternative splicing results in multiple transcriptvariants encoding different isoforms.


Malumbres, M., et al. Nat. Cell Biol. 11(11):1275-1276(2009)Liu, Y., et al. J. Biol. Chem. 281(15):9852-9858(2006)Palmer, K.J., et al. J. Cell. Sci. 118 (PT 17), 3839-3847 (2005) :Graeser, R., et al. J. Cell. Sci. 115 (PT 17), 3479-3490 (2002) :Esposito, T., et al. Genomics 43(2):183-190(1997)

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$ 80.00
Cat# BP11314a
Availability: In Stock
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