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PHOX2B Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q99453
Clone Names 90713162
Peptide ID 90713162
Additional Information
Gene ID 8929
Other Names Paired mesoderm homeobox protein 2B, Neuroblastoma Phox, NBPhox, PHOX2B homeodomain protein, Paired-like homeobox 2B, PHOX2B, PMX2B
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PMX2B
Function Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum- response element.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}
Tissue Location Expressed in neuroblastoma, brain and adrenal gland
Research Areas
Citations (0)

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The DNA-associated protein encoded by this gene is amember of the paired family of homeobox proteins localized to thenucleus. The protein functions as a transcription factor involvedin the development of several major noradrenergic neuronpopulations and the determination of neurotransmitter phenotype.The gene product is linked to enhancement of secondmessenger-mediated activation of the dopamine beta-hydroylase,c-fos promoters and several enhancers, including cyclicamp-response element and serum-response element. [provided byRefSeq].


Rudzinski, E., et al. Pediatr. Dev. Pathol. 13(4):291-299(2010)Janoueix-Lerosey, I., et al. Oncogene 29(11):1566-1579(2010)Tu, E., et al. Hum. Pathol. 41(3):392-400(2010)Arai, H., et al. J. Hum. Genet. 55(1):4-7(2010)Dubreuil, V., et al. J. Neurosci. 29(47):14836-14846(2009)

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$ 80.00
Cat# BP11341c
Availability: In Stock
Bulk Size
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