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CPT1C Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8TCG5
Clone Names 80410146
Peptide ID 80410146
Additional Information
Gene ID 126129
Other Names Carnitine O-palmitoyltransferase 1, brain isoform, CPT1-B, CPT IC, Carnitine O-palmitoyltransferase I, brain isoform, CPTI-B, Carnitine palmitoyltransferase 1C, CPT1C, CATL1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPT1C
Synonyms CATL1
Function May play a role in lipid metabolic process.
Cellular Location Mitochondrion outer membrane; Multi-pass membrane protein. Cell junction, synapse {ECO:0000250|UniProtKB:Q8BGD5}. Cell projection, dendrite. Cell projection, axon. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8BGD5}. Note=Localized in the soma and dendritic and axonal projections.
Tissue Location Expressed predominantly in brain and testis. Expressed in motor neurons.
Research Areas
Citations (0)

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The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Roomets, E., et al. Invest. Ophthalmol. Vis. Sci. 49(4):1660-1664(2008)Sierra, A.Y., et al. J. Biol. Chem. 283(11):6878-6885(2008)Price, N., et al. Genomics 80(4):433-442(2002)

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$ 80.00
Cat# BP11459b
Availability: In Stock
Bulk Size
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