|Other Names||Serpin B4, Leupin, Peptidase inhibitor 11, PI-11, Squamous cell carcinoma antigen 2, SCCA-2, SERPINB4, PI11, SCCA2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May act as a protease inhibitor to modulate the host immune response against tumor cells.|
|Cellular Location||Cytoplasm. Note=Seems to also be secreted in plasma by cancerous cells but at a low level|
|Tissue Location||Squamous cells.|
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Provided below are standard protocols that you may find useful for product applications.
SPB4 may act as a protease inhibitor to modulate the host immune response against tumor cells.
Murakami, A., et al. Int. J. Oncol. 36(6):1395-1400(2010)Higgins, W.J., et al. J. Biol. Chem. 285(6):3722-3729(2010)Villano, G., et al. Int. J. Mol. Med. 25(1):137-143(2010)Ahmed, S.T., et al. Biochem. Biophys. Res. Commun. 378(4):821-825(2009)Yamane, Y., et al. Int. Arch. Allergy Immunol. 150(1):89-101(2009)
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