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OBFC2B Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9BQ15
Clone Names 100126168
Peptide ID 100126168
Additional Information
Gene ID 79035
Other Names SOSS complex subunit B1, Nucleic acid-binding protein 2, Oligonucleotide/oligosaccharide-binding fold-containing protein 2B, Sensor of single-strand DNA complex subunit B1, Sensor of ssDNA subunit B1, SOSS-B1, Single-stranded DNA-binding protein 1, hSSB1, NABP2, OBFC2B, SSB1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NABP2
Synonyms OBFC2B, SSB1
Function Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
Cellular Location Nucleus Note=Localizes to nuclear foci following DNA damage. Foci formation is not cell-cycle dependent. Partial colocalization with RAD51 after ionizing radiation treatment
Research Areas
Citations (0)

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Single-stranded DNA (ssDNA)-binding proteins, such asOBFC2B, are ubiquitous and essential for a variety of DNA metabolicprocesses, including replication, recombination, and detection andrepair of damage (Richard et al., 2008 [PubMed 18449195]).[suppliedby OMIM].


Skaar, J.R., et al. J. Cell Biol. 187(1):25-32(2009)Li, Y., et al. J. Biol. Chem. 284(35):23525-23531(2009)Huang, J., et al. Mol. Cell 35(3):384-393(2009)Richard, D.J., et al. Nature 453(7195):677-681(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)

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$ 80.00
Cat# BP11591b
Availability: In Stock
Bulk Size
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