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KCTD8 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q6ZWB6
Clone Names 100126311
Peptide ID 100126311
Additional Information
Other Names BTB/POZ domain-containing protein KCTD8, KCTD8
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCTD8
Function Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).
Cellular Location Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane EMBL; AK123347; BAC85588.1; -; mRNA EMBL; BC132743; AAI32744.1; -; mRNA EMBL; BC136793; AAI36794.1; -; mRNA CCDS; CCDS3467.1; - RefSeq; NP_938167.1; NM_198353.2 UniGene; Hs.479644; - ProteinModelPortal; Q6ZWB6; - SMR; Q6ZWB6; - BioGrid; 132113; 2 CORUM; Q6ZWB6; - IntAct; Q6ZWB6; 2 GuidetoPHARMACOLOGY; 1917; - iPTMnet; Q6ZWB6; - PhosphoSitePlus; Q6ZWB6; - BioMuta; KCTD8; - DMDM; 74749707; - EPD; Q6ZWB6; - MaxQB; Q6ZWB6; - PaxDb; Q6ZWB6; - PeptideAtlas; Q6ZWB6; - PRIDE; Q6ZWB6; - ProteomicsDB; 68472; - DNASU; 386617; - Ensembl; ENST00000360029; ENSP00000353129; ENSG00000183783 GeneID; 386617; - KEGG; hsa:386617; - UCSC; uc003gwu.4; human CTD; 386617; - EuPathDB; HostDB:ENSG00000183783.6; - GeneCards; KCTD8; - HGNC; HGNC:22394; KCTD8 HPA; HPA031562; - neXtProt; NX_Q6ZWB6; - OpenTargets; ENSG00000183783; - PharmGKB; PA134909779; - eggNOG; KOG2723; Eukaryota eggNOG; ENOG410Z155; LUCA GeneTree; ENSGT00760000119013; - HOGENOM; HOG000041197; - HOVERGEN; HBG052218; - InParanoid; Q6ZWB6; - KO; K21918; - OMA; DHEERKH; - OrthoDB; EOG091G0P3F; - PhylomeDB; Q6ZWB6; - TreeFam; TF315332; - ChiTaRS; KCTD8; human GenomeRNAi; 386617; - PRO; PR:Q6ZWB6; - Proteomes; UP000005640; Chromosome 4 Bgee; ENSG00000183783; - CleanEx; HS_KCTD8; - ExpressionAtlas; Q6ZWB6; baseline and differential GO; GO:0030054; C:cell junction; IEA:UniProtKB-KW GO; GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell GO; GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell GO; GO:0043235; C:receptor complex; IEA:Ensembl GO; GO:0051260; P:protein homooligomerization; IEA:InterPro GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:Ensembl InterPro; IPR000210; BTB/POZ_dom InterPro; IPR011333; SKP1/BTB/POZ_sf InterPro; IPR003131; T1-type_BTB Pfam; PF02214; BTB_2; 1 SMART; SM00225; BTB; 1 SUPFAM; SSF54695; SSF54695; 1 2: Evidence at transcript level; Cell junction; Cell membrane; Complete proteome; Membrane; Methylation; Phosphoprotein; Polymorphism; Postsynaptic cell membrane; Reference proteome; Synapse CHAIN 1 473 BTB/POZ domain-containing protein KCTD8 /FTId=PRO_0000251481 DOMAIN 44 122 BTB COMPBIAS 21 25 Poly-Ser COMPBIAS 194 200 Poly-Gly MOD_RES 78 78 Phosphoserine {ECO:0000250|UniProtKB:Q50H33} MOD_RES 80 80 Omega-N-methylarginine {ECO:0000250|UniProtKB:Q50H33} MOD_RES 410 410 Phosphoserine {ECO:0000250|UniProtKB:Q50H33} VARIANT 329 329 P -> L (in dbSNP:rs13115990) /FTId=VAR_027692 SEQUENCE 473 AA; 52440 MW; D5AA3F75716D3715 CRC64; MALKDTGSGG STILPISEMV SSSSSPGASA AAAPGPCAPS PFPEVVELNV GGQVYVTKHS TLLSVPDSTL ASMFSPSSPR GGARRRGELP RDSRARFFID RDGFLFRYVL DYLRDKQLAL PEHFPEKERL LREAEYFQLT DLVKLLSPKV TKQNSLNDEG CQSDLEDNVS QGSSDALLLR GAAAAVPSGP GAHGGGGGGG AQDKRSGFLT LGYRGSYTTV RDNQADAKFR RVARIMVCGR IALAKEVFGD TLNESRDPDR QPEKYTSRFY LKFTYLEQAF DRLSEAGFHM VACNSSGTAA FVNQYRDDKI WSSYTEYIFF RPPQKIVSPK QEHEDRKHDK VTDKGSESGT SCNELSTSSC DSHSEASTPQ DNPSSAQQAT AHQPNTLTLD RPSKKAPVQW IPPPDKRRNS ELFQTLISKS RETNLSKKKV CEKLSVEEEM KKCIQDFKKI HIPDYFPERK RQWQSELLQK YGL
Research Areas
Citations (0)

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Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).


Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)

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$ 80.00
Cat# BP11599b
Availability: In Stock
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