|Other Names||Tubulin-specific chaperone A, TCP1-chaperonin cofactor A, Tubulin-folding cofactor A, CFA, TBCA|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Tubulin-folding protein; involved in the early step of the tubulin folding pathway.|
|Cellular Location||Cytoplasm, cytoskeleton.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The product of this gene is one of four proteins(cofactors A, D, E, and C) involved in the pathway leading tocorrectly folded beta-tubulin from folding intermediates. CofactorsA and D are believed to play a role in capturing and stabilizingbeta-tubulin intermediates in a quasi-native confirmation. CofactorE binds to the cofactor D/beta-tubulin complex; interaction withcofactor C then causes the release of beta-tubulin polypeptidesthat are committed to the native state. This gene encodeschaperonin cofactor A.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)Bruneel, A., et al. Proteomics 5(15):3876-3884(2005)Nolasco, S., et al. FEBS Lett. 579(17):3515-3524(2005)Guasch, A., et al. J. Mol. Biol. 318(4):1139-1149(2002)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.