|Other Names||Glutamyl aminopeptidase, EAP, Aminopeptidase A, AP-A, Differentiation antigen gp160, CD249, ENPEP|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulates central hypertension through its calcium- modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.|
|Cellular Location||Cell membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed in choriocarcinoma cancer cell lines (at protein level) (PubMed:10692253). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues|
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Provided below are standard protocols that you may find useful for product applications.
ENPEP appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)Rose, J. Phd, et al. Mol. Med. (2010) In press :Perez, I., et al. Head Neck 31(10):1335-1340(2009)Sevalle, J., et al. J. Neurochem. 109(1):248-256(2009)Teranishi, J., et al. Prostate 68(15):1666-1673(2008)
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