|Other Names||Kinesin light chain 2, KLC 2, KLC2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton.|
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Provided below are standard protocols that you may find useful for product applications.
Kinesin is a molecular motor that generates ATP-dependentmovement of vesicles and organelles along microtubules. Kinesinconsists of 2 light chains, such as KLC2, and 2 heavy chains (seeKIF5B; MIM 602809) in a 1:1 stoichiometric ratio (Rahman et al.,1998 [PubMed 9624122]).
Trejo, H.E., et al. FASEB J. 24(2):374-382(2010)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)
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