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FCN3 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O75636
Clone Names 100318091
Peptide ID 100318091
Additional Information
Gene ID 8547
Other Names Ficolin-3, Collagen/fibrinogen domain-containing lectin 3 p35, Collagen/fibrinogen domain-containing protein 3, Hakata antigen, FCN3, FCNH, HAKA1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FCN3
Synonyms FCNH, HAKA1
Function May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota.
Cellular Location Secreted. Note=Found in blood plasma, bronchus, alveolus and bile duct
Tissue Location Liver and lung. In liver it is produced by bile duct epithelial cells and hepatocytes. In lung it is produced by both ciliated bronchial epithelial cells and type II alveolar epithelial cells.
Research Areas
Citations (0)

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Ficolins are a group of proteins which consist of acollagen-like domain and a fibrinogen-like domain. In human serum,there are two types of ficolins, both of which have lectinactivity. The protein encoded by this gene is a thermolabilebeta-2-macroglycoprotein found in all human serum and is a memberof the ficolin/opsonin p35 lectin family. The protein, which wasinitially identified based on its reactivity with sera frompatients with systemic lupus erythematosus, has been shown to havea calcium-independent lectin activity. The protein can activate thecomplement pathway in association with MASPs and sMAP, therebyaiding in host defense through the activation of the lectinpathway. Alternative splicing occurs at this locus and twovariants, each encoding a distinct isoform, have been identified.


Davila, S., et al. Genes Immun. 11(3):232-238(2010)Andersen, T., et al. J. Rheumatol. 36(4):757-759(2009)Ruskamp, J.M., et al. Clin. Exp. Immunol. 155(3):433-440(2009)Lacroix, M., et al. J. Immunol. 182(1):456-465(2009)Munthe-Fog, L., et al. Mol. Immunol. 45(9):2660-2666(2008)

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$ 99.00
Cat# BP12561b
Availability: In Stock
Bulk Size
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