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RIC3 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q7Z5B4
Clone Names 100324058
Peptide ID 100324058
Additional Information
Gene ID 79608
Other Names Protein RIC-3, Resistant to inhibitor of cholinesterase 3, RIC3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RIC3
Function Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotoninergic 5- HT3 receptors, and of heteromeric acetylcholine receptors alpha- 3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4.
Cellular Location Isoform 1: Endoplasmic reticulum membrane; Single-pass membrane protein
Tissue Location Broadly expressed, with high levels in muscle, brain, heart, pancreas and testis. In the central nervous system, highest levels are detected in the cerebellum and pituitary gland Over-expressed in brains from patients with bipolar disease or schizophrenia. Isoform 5 is predominantly expressed in the brain
Research Areas
Citations (0)

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RIC3 is a protein associated with nicotinic acetylcholinereceptors (nAChRs), neurotransmitter-gated ion channels expressedat the neuromuscular junction and within the central and peripheralnervous systems, that can enhance functional expression of multiplenAChR subtypes (Lansdell et al., 2005 [PubMed 16120769]).[suppliedby OMIM].


Walstab, J., et al. J. Biol. Chem. 285(35):26956-26965(2010)Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Seredenina, T., et al. Biosci. Rep. 28(6):299-306(2008)Roncarati, R., et al. Assay Drug Dev Technol 6(2):181-193(2008)

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$ 99.00
Cat# BP12721b
Availability: In Stock
Bulk Size
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