|Other Names||Voltage-dependent calcium channel gamma-4 subunit, Neuronal voltage-gated calcium channel gamma-4 subunit, Transmembrane AMPAR regulatory protein gamma-4, TARP gamma-4, CACNG4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (PubMed:21127204). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization (PubMed:21172611).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Detected in heart left ventricle.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a type I transmembraneAMPA receptor regulatory protein (TARP). TARPs regulate bothtrafficking and channel gating of the AMPA receptors. This gene ispart of a functionally diverse eight-member protein subfamily ofthe PMP-22/EMP/MP20 family and is located in a cluster with twofamily members, a type II TARP and a calcium channel gamma subunit.
Sager, C., et al. Neuroscience 158(1):45-54(2009)Chen, R.S., et al. Cell Biochem. Biophys. 47(2):178-186(2007)Moss, F.J., et al. BMC Neurosci 4, 23 (2003) :Chu, P.J., et al. Gene 280 (1-2), 37-48 (2001) :Burgess, D.L., et al. Genomics 71(3):339-350(2001)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.