|Other Names||Carbonyl reductase [NADPH] 3, NADPH-dependent carbonyl reductase 3, CBR3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro).|
|Tissue Location||Detected in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis.|
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Provided below are standard protocols that you may find useful for product applications.
Carbonyl reductase 3 catalyzes the reduction of a largenumber of biologically and pharmacologically active carbonylcompounds to their corresponding alcohols. The enzyme isclassified as a monomeric NADPH-dependent oxidoreductase. CBR3contains three exons spanning 11.2 kilobases and is closely linkedto another carbonyl reductase gene - CBR1.
Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)Zhang, J., et al. Pharm. Res. 26(9):2209-2215(2009)Choi, J.Y., et al. Clin. Cancer Res. 15(16):5258-5266(2009)Pilka, E.S., et al. PLoS ONE 4 (10), E7113 (2009) :
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