|Other Names||N-formyl peptide receptor 3, FMLP-related receptor II, FMLP-R-II, Formyl peptide receptor-like 2, FPR3, FPRH1, FPRL2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Davila, S., et al. Genes Immun. 11(3):232-238(2010)Kim, S.D., et al. J. Immunol. 183(9):5511-5517(2009)Devosse, T., et al. J. Immunol. 182(8):4974-4984(2009)Lambert, N.A. Sci Signal 1 (25), RE5 (2008) :Lee, H.Y., et al. Biochem. Biophys. Res. Commun. 359(4):985-990(2007)
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