|Other Names||MAGUK p55 subfamily member 3, Discs large homolog 3, Protein MPP3, MPP3, DLG3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene product is a member of a family ofmembrane-associated proteins termed MAGUKs (membrane-associatedguanylate kinase homologs). MAGUKs interact with the cytoskeletonand regulate cell proliferation, signaling pathways, andintracellular junctions. This protein contains a conservedsequence, called the SH3 (src homology 3) motif, found in severalother proteins that associate with the cytoskeleton and aresuspected to play important roles in signal transduction.Alternatively spliced transcript variants have been identified. Onetranscript variant is experimentally supported, but it doesn'tencode a protein.
Qin, L., et al. Zhonghua Gan Zang Bing Za Zhi 15(7):509-512(2007)Kantardzhieva, A., et al. FEBS J. 273(6):1152-1165(2006)Stelzl, U., et al. Cell 122(6):957-968(2005)Fukuhara, H., et al. Oncogene 22(40):6160-6165(2003)Shin, B.K., et al. J. Biol. Chem. 278(9):7607-7616(2003)
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