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REPS2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8NFH8
Clone Names 100324150
Peptide ID 100324150
Additional Information
Gene ID 9185
Other Names RalBP1-associated Eps domain-containing protein 2, Partner of RalBP1, RalBP1-interacting protein 2, REPS2, POB1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13131a was selected from the N-term region of REPS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name REPS2
Synonyms POB1
Function Involved in growth factor signaling through its influence on the Ral signaling pathway.
Cellular Location Cytoplasm.
Tissue Location Expressed at high levels in the cerebrum, cerebellum, lung, kidney, and testis. Weakly expressed in the kidney. Relatively highly expressed in androgen-dependent as compared to androgen-independent prostate cancer cell lines and xenografts. Isoform 2 is down-regulated during progression of prostate cancer
Research Areas
Citations (0)

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The product of this gene is part of a protein complex thatregulates the endocytosis of growth factor receptors. The encodedprotein directly interacts with a GTPase activating protein thatfunctions downstream of the small G protein Ral. Its expression cannegatively affect receptor internalization and inhibit growthfactor signaling. Multiple transcript variants encoding differentisoforms have been found for this gene.


Doolan, P., et al. Tumour Biol. 30(4):200-209(2009)Singhal, S.S., et al. J. Biol. Chem. 283(28):19714-19729(2008)Yadav, S., et al. Biochem. Biophys. Res. Commun. 328(4):1003-1009(2005)Oosterhoff, J.K., et al. Int. J. Cancer 113(4):561-567(2005)Penninkhof, F., et al. Oncogene 23(33):5607-5615(2004)

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$ 80.00
Cat# BP13131a
Availability: In Stock
Bulk Size
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