|Other Names||Transformer-2 protein homolog alpha, TRA-2 alpha, TRA2-alpha, Transformer-2 protein homolog A, TRA2A|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13223c was selected from the Center region of TRA2A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the transformer 2 homolog familyand encodes a protein with two RS domains and an RRM (RNArecognition motif) domain. This phosphorylated nuclear proteinbinds to specific RNA sequences and plays a role in the regulationof pre-mRNA splicing. Several alternatively spliced transcriptvariants of this gene have been described; however, the full-lengthnature of some of these variants has not been determined. [providedby RefSeq].
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)Gevaert, K., et al. Proteomics 5(14):3589-3599(2005)
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