|Other Names||SEC14-like protein 4, Tocopherol-associated protein 3, SEC14L4, TAP3|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13245a was selected from the N-term region of SEC14L4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is highly similar to theprotein encoded by the Saccharomyces cerevisiae SEC14 gene. TheSEC14 protein is a phophatidylinositol transfer protein that isessential for biogenesis of Golgi-derived transport vesicles, andthus is required for the export of yeast secretory proteins fromthe Golgi complex. The specific function of this protein has notyet been determined. Alternative splicing results in multipletranscript variants.
Mokashi, V., et al. Biochem. Biophys. Res. Commun. 316(3):688-692(2004)Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :Kempna, P., et al. Free Radic. Biol. Med. 34(11):1458-1472(2003)Dunham, I., et al. Nature 402(6761):489-495(1999)
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