|Other Names||Autophagy-related protein 101, ATG101, C12orf44|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13300a was selected from the N-term region of C12orf44. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.|
|Cellular Location||Cytoplasm. Preautophagosomal structure Note=Under starvation conditions, it is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.|
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Provided below are standard protocols that you may find useful for product applications.
C12orf44 is a autophagy factor required for autophagosome formation.
Hosokawa, N., et al. Autophagy 5(7):973-979(2009)Mercer, C.A., et al. Autophagy 5(5):649-662(2009)Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
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