|Other Names||Dyslexia-associated protein KIAA0319-like protein, KIAA0319L, KIAA1837|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13352b was selected from the C-term region of KIAA0319L. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Possible role in axon guidance through interaction with RTN4R.|
|Cellular Location||Cytoplasmic granule membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Traffics from the plasma membrane to the trans-Golgi network.|
|Tissue Location||Expressed in cortical neurons in the brain cortex (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a candidate gene for dyslexia susceptibility.
Yoshida, T., et al. Int. J. Mol. Med. 24(2):233-246(2009)Couto, J.M., et al. J. Neurogenet. 22(4):295-313(2008)
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