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ALPP Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P05187
Clone Names 101229019
Peptide ID 101229019
Additional Information
Gene ID 250
Other Names Alkaline phosphatase, placental type, Alkaline phosphatase Regan isozyme, Placental alkaline phosphatase 1, PLAP-1, ALPP, PLAP
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13553c was selected from the Center region of ALPP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PLAP
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Location Detected in placenta (at protein level).
Research Areas
Citations (0)

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There are at least four distinct but related alkalinephosphatases: intestinal, placental, placental-like, andliver/bone/kidney (tissue non-specific). The first three arelocated together on chromosome 2 while the tissue non-specific formis located on chromosome 1. The product of this gene is a membranebound glycosylated enzyme, also referred to as the heat stableform, that is expressed primarily in the placenta although it isclosely related to the intestinal form of the enzyme as well as tothe placental-like form. The coding sequence for this form ofalkaline phosphatase is unique in that the 3' untranslated regioncontains multiple copies of an Alu family repeat. In addition, thisgene is polymorphic and three common alleles (type 1, type 2 andtype 3) for this form of alkaline phosphatase have been wellcharacterized.


Stec, B., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (PT 8), 866-870 (2010) :Wang, F., et al. Am. J. Surg. Pathol. 33(10):1529-1539(2009)Estrada, K., et al. Hum. Mol. Genet. 18(18):3516-3524(2009)Zhu, J.F., et al. Zhonghua Wai Ke Za Zhi 47(5):381-384(2009)Roberson, J.R., et al. Pediatr Blood Cancer 51(6):840-842(2008)

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$ 99.00
Cat# BP13553c
Availability: In Stock
Bulk Size
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