- CITATIONS: 1
|Other Names||Inactive rhomboid protein 2, iRhom2, Rhomboid 5 homolog 2, Rhomboid family member 2, Rhomboid veinlet-like protein 5, Rhomboid veinlet-like protein 6, RHBDF2, IRHOM2, RHBDL5, RHBDL6|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13588a was selected from the N-term region of RHBDF2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||IRHOM2, RHBDL5, RHBDL6|
|Function||Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane|
|Tissue Location||Found in the epidermis and esophageal epithelium.|
Provided below are standard protocols that you may find useful for product applications.
Not expected to have protease activity (By similarity).
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