|Other Names||Synaptophysin, Major synaptic vesicle protein p38, SYP|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13606b was selected from the C-term region of SYP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi- pass membrane protein. Cell junction, synapse, synaptosome|
|Tissue Location||Expressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3|
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Provided below are standard protocols that you may find useful for product applications.
Synaptophysin (p38) is an integral membrane protein ofsmall synaptic vesicles in brain and endocrine cells.[supplied byOMIM].
Ishida, M., et al. Oncol. Rep. 22(4):733-737(2009)Sterlacci, W., et al. Virchows Arch. 455(2):125-132(2009)Head, E., et al. Neurobiol. Aging 30(7):1125-1134(2009)Gulubova, M., et al. J. Gastroenterol. Hepatol. 23(10):1574-1585(2008)Glantz, L.A., et al. Neuroscience 149(3):582-591(2007)
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