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QSOX2 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q6ZRP7
Clone Names 100416054
Peptide ID 100416054
Additional Information
Gene ID 169714
Other Names Sulfhydryl oxidase 2, Neuroblastoma-derived sulfhydryl oxidase, Quiescin Q6-like protein 1, QSOX2, QSCN6L1, SOXN
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13657c was selected from the Center region of QSOX2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name QSOX2
Synonyms QSCN6L1, SOXN
Function Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. Also seems to play a role in regulating the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis.
Cellular Location Membrane; Single-pass membrane protein Secreted. Cell membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Note=Seems to be predominantly targeted to the nuclear and outer plasma membrane
Tissue Location Expressed in pancreas, brain, placenta, kidney, heart and fetal tissues. Weakly expressed in lung, liver and skeletal muscles.
Research Areas
Citations (0)

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QSOX2 is a member of the sulfhydryl oxidase/quiescin-6(Q6) family (QSOX1; MIM 603120) that regulates the sensitization ofneuroblastoma cells for IFN-gamma (IFNG; MIM 147570)-induced celldeath (Wittke et al., 2003 [PubMed 14633699]).


Okada, Y., et al. Hum. Mol. Genet. 19(11):2303-2312(2010)Olsen, J.V., et al. Cell 127(3):635-648(2006)Humphray, S.J., et al. Nature 429(6990):369-374(2004)Wittke, I., et al. Cancer Res. 63(22):7742-7752(2003)Thorpe, C., et al. Arch. Biochem. Biophys. 405(1):1-12(2002)

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$ 80.00
Cat# BP13657c
Availability: In Stock
Bulk Size
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