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CELA3B Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P08861
Clone Names 100427308
Peptide ID 100427308
Additional Information
Gene ID 23436
Other Names Chymotrypsin-like elastase family member 3B, Elastase IIIB, Elastase-3B, Protease E, CELA3B, ELA3B
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13770a was selected from the N-term region of CELA3B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ELA3B
Function Efficient protease with alanine specificity but only little elastolytic activity.
Tissue Location Pancreas. Not detectable in keratinocytes.
Research Areas
Citations (0)

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Elastases form a subfamily of serine proteases thathydrolyze many proteins in addition to elastin. Humans have sixelastase genes which encode the structurally similar proteinselastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase3B has little elastolytic activity. Like most of the humanelastases, elastase 3B is secreted from the pancreas as a zymogenand, like other serine proteases such as trypsin, chymotrypsin andkallikrein, it has a digestive function in the intestine. Elastase3B preferentially cleaves proteins after alanine residues. Elastase3B may also function in the intestinal transport and metabolism ofcholesterol. Both elastase 3A and elastase 3B have been referred toas protease E and as elastase 1, and excretion of this protein infecal material is frequently used as a measure of pancreaticfunction in clinical assays.


Gao, J., et al. Oncol. Rep. 23(6):1683-1692(2010)Teichmann, J., et al. Eur. J. Med. Res. 13(12):563-567(2008)Hahn, J.U., et al. Pancreas 36(3):274-278(2008)Mann, S.T., et al. Eur. J. Med. Res. 13(2):68-72(2008)Vesterhus, M., et al. Diabetes Care 31(2):306-310(2008)

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$ 80.00
Cat# BP13770a
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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