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RLN1/RLN2 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P04808
Clone Names 100430116
Peptide ID 100430116
Additional Information
Gene ID 6013
Other Names Prorelaxin H1, Relaxin B chain, Relaxin A chain, RLN1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13864b was selected from the C-term region of RLN1/RLN2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RLN1
Function Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
Cellular Location Secreted.
Tissue Location Prostate. Not expressed in placenta, decidua or ovary.
Research Areas
Citations (0)

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Relaxins are known endocrine and autocrine/paracrinehormones, belonging to the insulin gene superfamily. In the humanthere are three non-allelic relaxin genes, RLN1, RLN2 and RLN3.RLN1 and RLN2 share high sequence homology. This encoded protein issynthesized as a single-chain polypeptide but the active formconsists of an A chain and a B chain linked by disulfide bonds;however, their exact cleavage sites have not been described.Relaxin is produced by the ovary, and targets the mammalianreproductive system to ripen the cervix, elongate the pubicsymphysis and inhibit uterine contraction. It may have additionalroles in enhancing sperm motility, regulating blood pressure,controlling heart rate and releasing oxytocin and vasopressin. Thisgene has multiple polyadenylation sites. There are multiplealternatively spliced transcript variants described for this genebut their full length nature is not known yet. [provided byRefSeq].


Radestock, Y., et al. Mol. Cancer Res. 8(4):494-506(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Ferlin, A., et al. Bone 46(2):504-513(2010)Vogel, I., et al. In Vivo 23(6):1005-1009(2009)Anumba, D.O., et al. Eur. J. Obstet. Gynecol. Reprod. Biol. 147(1):41-45(2009)

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$ 80.00
Cat# BP13864b
Availability: In Stock
Bulk Size
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