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ADAM11 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O75078
Clone Names 100507070
Peptide ID 100507070
Additional Information
Gene ID 4185
Other Names Disintegrin and metalloproteinase domain-containing protein 11, ADAM 11, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein, MDC, ADAM11, MDC
Target/Specificity The synthetic peptide sequence used to generate the antibody AP14066a was selected from the N-term region of ADAM11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADAM11
Synonyms MDC
Function Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed predominantly in brain. Slightly detected or not at all in other tissues
Research Areas
Citations (0)

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This gene encodes a member of the ADAM (a disintegrin andmetalloprotease) protein family. Members of this family aremembrane-anchored proteins structurally related to snake venomdisintegrins, and have been implicated in a variety of biologicalprocesses involving cell-cell and cell-matrix interactions,including fertilization, muscle development, and neurogenesis. Thisgene represents a candidate tumor supressor gene for human breastcancer based on its location within a minimal region of chromosome17q21 previously defined by tumor deletion mapping. [provided byRefSeq].


Fu, G.K., et al. Genomics 84(1):205-210(2004)Hillman, R.T., et al. Genome Biol. 5 (2), R8 (2004) :Shea, S.H., et al. Behav. Genet. 31(2):231-239(2001)Sagane, K., et al. Biochem. J. 334 (PT 1), 93-98 (1998) :Wolfsberg, T.G., et al. J. Cell Biol. 131(2):275-278(1995)

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$ 80.00
Cat# BP14066a
Availability: In Stock
Bulk Size
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