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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   HNRPF Antibody (N-term) Blocking peptide   

HNRPF Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P52597
Clone Names 81028063
Peptide ID 81028063
Additional Information
Gene ID 3185
Other Names Heterogeneous nuclear ribonucleoprotein F, hnRNP F, Nucleolin-like protein mcs94-1, Heterogeneous nuclear ribonucleoprotein F, N-terminally processed, HNRNPF, HNRPF
Target/Specificity The synthetic peptide sequence used to generate the antibody AP14092a was selected from the N-term region of HNRPF. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HNRPF
Function Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
Cellular Location Nucleus, nucleoplasm.
Tissue Location Expressed ubiquitously.
Research Areas
Citations (0)

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This gene belongs to the subfamily of ubiquitouslyexpressed heterogeneous nuclear ribonucleoproteins (hnRNPs). ThehnRNPs are RNA binding proteins that complex with heterogeneousnuclear RNA (hnRNA). These proteins are associated with pre-mRNAsin the nucleus and regulate alternative splicing, polyadenylation,and other aspects of mRNA metabolism and transport. While all ofthe hnRNPs are present in the nucleus, some seem to shuttle betweenthe nucleus and the cytoplasm. The hnRNP proteins have distinctnucleic acid binding properties. The protein encoded by this genehas three repeats of quasi-RRM domains that bind to RNAs which haveguanosine-rich sequences. This protein is very similar to thefamily member hnRPH. Multiple alternatively spliced variants,encoding the same protein, have been identified. [provided byRefSeq].


Dominguez, C., et al. Nat. Struct. Mol. Biol. 17(7):853-861(2010)Goh, E.T., et al. J. Biol. Chem. 285(22):17065-17076(2010)Van Dusen, C.M., et al. Mol. Cell. Biol. 30(10):2552-2562(2010)Lee, J.H., et al. Virology 397(1):89-99(2010)Wang, E., et al. J. Biol. Chem. 284(17):11194-11204(2009)

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$ 80.00
Cat# BP14092a
Availability: In Stock
Bulk Size
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