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TMC6 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q7Z403
Clone Names 100507055
Peptide ID 100507055
Additional Information
Gene ID 11322
Other Names Transmembrane channel-like protein 6, Epidermodysplasia verruciformis protein 1, Protein LAK-4, TMC6, EVER1, EVIN1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMC6
Synonyms EVER1, EVIN1
Function Probable ion channel.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Expressed in placenta, prostate, testis, activated T-lymphocytes and lymphokine-activated killer (LAK) lymphocytes. {ECO:0000269|PubMed:12906855, ECO:0000269|Ref.3}
Research Areas
Citations (0)

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Epidermodysplasia verruciformis (EV) is an autosomalrecessive dermatosis characterized by abnormal susceptibility tohuman papillomaviruses (HPVs) and a high rate of progression tosquamous cell carcinoma on sun-exposed skin. EV is caused bymutations in either of two adjacent genes located on chromosome17q25.3. Both of these genes encode integral membrane proteins thatlocalize to the endoplasmic reticulum and are predicted to formtransmembrane channels. This gene encodes a transmembranechannel-like protein with 10 transmembrane domains and 2 leucinezipper motifs.


McDermott, D.F., et al. Pediatr Dermatol 26(3):306-310(2009)Lazarczyk, M., et al. J. Exp. Med. 205(1):35-42(2008)Zuo, Y.G., et al. J. Dermatol. Sci. 44(3):153-159(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Donfack, J., et al. Int. J. Pediatr. Otorhinolaryngol. 70(7):1235-1240(2006)

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$ 80.00
Cat# BP14212a
Availability: In Stock
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