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TMC8 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8IU68
Clone Names 100517185
Peptide ID 100517185
Additional Information
Gene ID 147138
Other Names Transmembrane channel-like protein 8, Epidermodysplasia verruciformis protein 2, TMC8, EVER2, EVIN2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMC8
Synonyms EVER2, EVIN2
Function Probable ion channel.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Expressed in placenta, prostate and testis.
Research Areas
Citations (0)

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Epidermodysplasia verruciformis (EV) is an autosomalrecessive dermatosis characterized by abnormal susceptibility tohuman papillomaviruses (HPVs) and a high rate of progression tosquamous cell carcinoma on sun-exposed skin. EV is caused bymutations in either of two adjacent genes located on chromosome17q25.3. Both of these genes encode integral membrane proteins thatlocalize to the endoplasmic reticulum and are predicted to formtransmembrane channels. This gene encodes a transmembranechannel-like protein with 8 predicted transmembrane domains and 3leucine zipper motifs.


McDermott, D.F., et al. Pediatr Dermatol 26(3):306-310(2009)Patel, A.S., et al. Int. J. Cancer 122(10):2377-2379(2008)Zavattaro, E., et al. J. Invest. Dermatol. 128(3):732-735(2008)Lazarczyk, M., et al. J. Exp. Med. 205(1):35-42(2008)Rady, P.L., et al. Br. J. Dermatol. 157(4):831-833(2007)

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$ 80.00
Cat# BP14243a
Availability: In Stock
Bulk Size
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