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GTF2A1L Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UNN4
Clone Names 100517148
Peptide ID 100517148
Additional Information
Gene ID 11036
Other Names TFIIA-alpha and beta-like factor, General transcription factor II A, 1-like factor, GTF2A1L, ALF, GTF2A1LF
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GTF2A1L
Synonyms ALF, GTF2A1LF
Function May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription.
Cellular Location Nucleus. Note=Mainly localizes in the annulus and partly in acrosomal cap area of spermatozoa
Tissue Location Testis specific. Detected in adult testis mostly in round and elongating spermatids (at protein level) Detected in testis.
Research Areas
Citations (0)

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The assembly and stability of the RNA polymerase IItranscription pre-initiation complex on a eukaryotic core promoterinvolve the effects of TFIIA on the interaction betweenTATA-binding protein (TBP) and DNA. This gene encodes a germcell-specific counterpart of the large (alpha/beta) subunit ofgeneral transcription factor TFIIA that is able to stabilize thebinding of TBP to DNA and may be uniquely important to testisbiology. Alternative splicing for this locus has been observed andtwo variants, encoding distinct isoforms, have been identified.Co-transcription of this gene and the neighboring upstream genegenerates a rare transcript (SALF), which encodes a fusion proteincomprised of sequence sharing identity with each individual geneproduct.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Kim, M., et al. J. Biol. Chem. 281(45):34288-34298(2006)Howe, M.L., et al. Stem Cells Dev. 15(2):175-190(2006)Huang, M., et al. Int. J. Mol. Med. 17(4):599-604(2006)Upadhyaya, A.B., et al. J. Biol. Chem. 277(37):34208-34216(2002)

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$ 99.00
Cat# BP14377b
Availability: In Stock
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