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MTMR2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q13614
Clone Names 100525066
Peptide ID 100525066
Additional Information
Gene ID 8898
Other Names Myotubularin-related protein 2, Phosphatidylinositol-3, 5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase, MTMR2, KIAA1073
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MTMR2
Synonyms KIAA1073
Function Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate (PubMed:11733541, PubMed:12668758, PubMed:21372139, PubMed:14690594). Binds phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate (By similarity). Stabilizes SBF2/MTMR13 at the membranes (By similarity). Specifically in peripheral nerves, stabilizes SBF2/MTMR13 protein (By similarity).
Cellular Location Cytoplasm. Early endosome membrane; Peripheral membrane protein Cytoplasm, perinuclear region. Cell projection, axon {ECO:0000250|UniProtKB:Q9Z2D1}. Endosome membrane {ECO:0000250|UniProtKB:Q9Z2D1}; Peripheral membrane protein. Note=Partly associated with membranes (PubMed:12668758, PubMed:15998640, PubMed:21372139). Localizes to vacuoles in hypo-osmotic conditions (By similarity) {ECO:0000250|UniProtKB:Q9Z2D1, ECO:0000269|PubMed:12668758, ECO:0000269|PubMed:15998640, ECO:0000269|PubMed:21372139}
Research Areas
Citations (0)

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This gene is a member of the myotubularin family. Theencoded protein possesses phosphatase activity towardsphosphatidylinositol-3-phosphate andphosphatidylinositol-3,5-bisphosphate. Mutations in this gene are acause of Charcot-Marie-Tooth disease type 4B, an autosomalrecessive demyelinating neuropathy. Multiple alternatively splicedtranscript variants have been found for this gene. [provided byRefSeq].


Kim, Y.C., et al. Proc. Natl. Acad. Sci. U.S.A. 106(20):8278-8283(2009)Lecompte, O., et al. Trends Biochem. Sci. 33(10):453-460(2008)Nicot, A.S., et al. Traffic 9(8):1240-1249(2008)Chojnowski, A., et al. Neurobiol. Dis. 26(2):323-331(2007)Previtali, S.C., et al. Expert Rev Mol Med 9(25):1-16(2007)

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$ 99.00
Cat# BP14408a
Availability: In Stock
Bulk Size
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