|Other Names||Kinesin heavy chain isoform 5C, Kinesin heavy chain neuron-specific 2, KIF5C, KIAA0531, NKHC2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in synaptic transmission (PubMed:24812067). Mediates dendritic trafficking of mRNAs (By similarity). Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton. Cell projection, dendrite. Note=Abundant in distal regions of dendrites.|
|Tissue Location||Highest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary|
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Provided below are standard protocols that you may find useful for product applications.
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.
Rose, J. Phd, et al. Mol. Med. (2010) In press :Wang, X., et al. Cell 136(1):163-174(2009)Schafer, B., et al. Cell. Mol. Life Sci. 66(2):339-349(2009)Schafer, B., et al. Biochem. Biophys. Res. Commun. 375(2):179-183(2008)Cho, K.I., et al. Traffic 8(12):1722-1735(2007)
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