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SNRPN Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P63162
Clone Names 100525161
Peptide ID 100525161
Additional Information
Gene ID 6638;8926
Other Names Small nuclear ribonucleoprotein-associated protein N, snRNP-N, Sm protein D, Sm-D, Sm protein N, Sm-N, SmN, Tissue-specific-splicing protein, SNRPN, HCERN3, SMN
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HCERN3, SMN
Function May be involved in tissue-specific alternative RNA processing events.
Cellular Location Nucleus.
Tissue Location Expressed in brain and lymphoblasts.
Research Areas
Citations (0)

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The protein encoded by this gene is one polypeptide of asmall nuclear ribonucleoprotein complex and belongs to the snRNPSMB/SMN family. The protein plays a role in pre-mRNA processing,possibly tissue-specific alternative splicing events. Althoughindividual snRNPs are believed to recognize specific nucleic acidsequences through RNA-RNA base pairing, the specific role of thisfamily member is unknown. The protein arises from a bicistronictranscript that also encodes a protein identified as the SNRPNupstream reading frame (SNURF). Multiple transcription initiationsites have been identified and extensive alternative splicingoccurs in the 5' untranslated region. Additional splice variantshave been described but sequences for the complete transcripts havenot been determined. The 5' UTR of this gene has been identified asan imprinting center. Alternative splicing or deletion caused by atranslocation event in this paternally-expressed region isresponsible for Angelman syndrome or Prader-Willi syndrome due toparental imprint switch failure.


Benetatos, L., et al. Leuk. Res. 34(2):148-153(2010)Kim, S.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (7), 1116-1125 (2008) :Horsthemke, B., et al. Am. J. Med. Genet. A 146A (16), 2041-2052 (2008) :Runte, M., et al. Hum. Mol. Genet. 10(23):2687-2700(2001)Kuslich, C.D., et al. Am. J. Hum. Genet. 64(1):70-76(1999)

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$ 80.00
Cat# BP14532a
Availability: In Stock
Bulk Size
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