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HYAL1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q12794
Clone Names 100318023
Peptide ID 100318023
Additional Information
Gene ID 3373
Other Names Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung carcinoma protein 1, LuCa-1, HYAL1, LUCA1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HYAL1
Synonyms LUCA1
Function May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth.
Cellular Location Secreted. Lysosome
Tissue Location Highly expressed in the liver, kidney and heart. Weakly expressed in lung, placenta and skeletal muscle. No expression detected in adult brain. Isoform 1 is expressed only in bladder and prostate cancer cells, G2/G3 bladder tumor tissues and lymph node specimens showing tumor invasive tumors cells. Isoform 3, isoform 4, isoform 5 and isoform 6 are expressed in normal bladder and bladder tumor tissues.
Research Areas
Citations (0)

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This gene encodes a lysosomal hyaluronidase.Hyaluronidases intracellularly degrade hyaluronan, one of the majorglycosaminoglycans of the extracellular matrix. Hyaluronan isthought to be involved in cell proliferation, migration anddifferentiation. This enzyme is active at an acidic pH and is themajor hyaluronidase in plasma. Mutations in this gene areassociated with mucopolysaccharidosis type IX, or hyaluronidasedeficiency. The gene is one of several related genes in a region ofchromosome 3p21.3 associated with tumor suppression. Multipletranscript variants encoding different isoforms have been found forthis gene.


Lanktree, M.B., et al. Blood 116(12):2160-2163(2010)Gasingirwa, M.C., et al. Biochem. J. 430(2):305-313(2010)Tzuman, Y.C., et al. Neoplasia 12(1):51-60(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Wang, X.Y., et al. Chin. Med. J. 122(11):1300-1304(2009)

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$ 80.00
Cat# BP14886b
Availability: In Stock
Bulk Size
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