|Other Names||Histone deacetylase complex subunit SAP130, 130 kDa Sin3-associated polypeptide, Sin3-associated polypeptide p130, SAP130|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.|
|Tissue Location||Expressed in various cancer cell ines.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
SAP130 is a subunit of the histone deacetylase (see HDAC1;MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex(Fleischer et al., 2003 [PubMed 12724404]).
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Truty, M.J., et al. J. Biol. Chem. 284(10):6291-6300(2009)Olsen, J.V., et al. Cell 127(3):635-648(2006)Fleischer, T.C., et al. Mol. Cell. Biol. 23(10):3456-3467(2003)Martinez, E., et al. Mol. Cell. Biol. 21(20):6782-6795(2001)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.