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SETD3 Blocking Peptide(C-term)

Synthetic peptide

     
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Product Information
Primary Accession Q86TU7
Other Accession NP_115609.2, NP_954574.1
Additional Information
Gene ID 84193
Other Names Histone-lysine N-methyltransferase setd3, SET domain-containing protein 3, SETD3, C14orf154
Target/Specificity The synthetic peptide sequence is selected from aa 571-585 of HUMAN SETD3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SETD3
Function Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73' (PubMed:30526847, Ref.13). Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery (Ref.13). Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin (Ref.13).
Cellular Location Cytoplasm {ECO:0000269|PubMed:28442573, ECO:0000269|Ref.13}. Nucleus Note=Localizes mainly in the cytoplasm
Research Areas
Citations (0)

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Background

SETD3 contains 1 SET domain. The function of the SETD3 protein remains unknown. There are 3 isoforms produced by alternative splicing.

References

Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)
Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)
Harrington, J.J., et al. Nat. Biotechnol. 19(5):440-445(2001)

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$ 99.00
Cat# BP19739B
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