Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   SERBP1 Blocking Peptide (Center)   

SERBP1 Blocking Peptide (Center)

Synthetic peptide

Product Information
Primary Accession Q8NC51
Additional Information
Other Names Plasminogen activator inhibitor 1 RNA-binding protein, PAI1 RNA-binding protein 1, PAI-RBP1, SERPINE1 mRNA-binding protein 1, SERBP1, PAIRBP1
Target/Specificity The synthetic peptide sequence is selected from aa 149-163 of HUMAN SERBP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SERBP1 (HGNC:17860)
Synonyms PAIRBP1
Function May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation (PubMed:28695742).
Cellular Location Cytoplasm. Nucleus Cytoplasm, perinuclear region
Tissue Location Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain EMBL; AF151813; AAD34050.1; -; mRNA EMBL; AL080119; CAB45718.1; -; mRNA EMBL; AK074970; BAC11324.1; -; mRNA EMBL; CR457383; CAG33664.1; -; mRNA EMBL; AL590559; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC003049; AAH03049.1; -; mRNA EMBL; BC008045; AAH08045.1; -; mRNA EMBL; BC017449; AAH17449.1; -; mRNA EMBL; BC019273; AAH19273.1; -; mRNA EMBL; BC020555; AAH20555.1; -; mRNA EMBL; BC002488; AAH02488.1; -; mRNA EMBL; BC026916; AAH26916.1; -; mRNA EMBL; AY032853; AAK51130.1; -; mRNA CCDS; CCDS30746.1; -. [Q8NC51-1] CCDS; CCDS30747.1; -. [Q8NC51-3] CCDS; CCDS30748.1; -. [Q8NC51-2] CCDS; CCDS639.1; -. [Q8NC51-4] PIR; T12456; T12456 RefSeq; NP_001018077.1; NM_001018067.1. [Q8NC51-1] RefSeq; NP_001018078.1; NM_001018068.1. [Q8NC51-2] RefSeq; NP_001018079.1; NM_001018069.1. [Q8NC51-3] RefSeq; NP_056455.3; NM_015640.3. [Q8NC51-4] UniGene; Hs.530412; - PDB; 4V6X; EM; 5.00 A; Ah=1-408 PDBsum; 4V6X; - ProteinModelPortal; Q8NC51; - BioGrid; 117571; 135 DIP; DIP-33819N; - IntAct; Q8NC51; 63 MINT; Q8NC51; - STRING; 9606.ENSP00000360034; - CarbonylDB; Q8NC51; - iPTMnet; Q8NC51; - PhosphoSitePlus; Q8NC51; - SwissPalm; Q8NC51; - BioMuta; SERBP1; - DMDM; 52783206; - EPD; Q8NC51; - jPOST; Q8NC51; - MaxQB; Q8NC51; - PaxDb; Q8NC51; - PeptideAtlas; Q8NC51; - PRIDE; Q8NC51; - ProteomicsDB; 72850; - ProteomicsDB; 72851; -. [Q8NC51-2] ProteomicsDB; 72852; -. [Q8NC51-3] ProteomicsDB; 72853; -. [Q8NC51-4] TopDownProteomics; Q8NC51-1; -. [Q8NC51-1] TopDownProteomics; Q8NC51-2; -. [Q8NC51-2] TopDownProteomics; Q8NC51-3; -. [Q8NC51-3] TopDownProteomics; Q8NC51-4; -. [Q8NC51-4] DNASU; 26135; - Ensembl; ENST00000361219; ENSP00000354591; ENSG00000142864. [Q8NC51-3] Ensembl; ENST00000370990; ENSP00000360029; ENSG00000142864. [Q8NC51-2] Ensembl; ENST00000370994; ENSP00000360033; ENSG00000142864. [Q8NC51-4] Ensembl; ENST00000370995; ENSP00000360034; ENSG00000142864. [Q8NC51-1] GeneID; 26135; - KEGG; hsa:26135; - UCSC; uc001ddv.4; human. [Q8NC51-1] CTD; 26135; - DisGeNET; 26135; - EuPathDB; HostDB:ENSG00000142864.14; - GeneCards; SERBP1; - HGNC; HGNC:17860; SERBP1 HPA; CAB026297; - HPA; HPA020559; - MIM; 607378; gene neXtProt; NX_Q8NC51; - OpenTargets; ENSG00000142864; - PharmGKB; PA413; - eggNOG; KOG2945; Eukaryota eggNOG; ENOG410YBHR; LUCA GeneTree; ENSGT00520000055591; - HOVERGEN; HBG056357; - InParanoid; Q8NC51; - KO; K13199; - OMA; QNRKREF; - OrthoDB; 1183388at2759; - PhylomeDB; Q8NC51; - TreeFam; TF318374; - ChiTaRS; SERBP1; human GeneWiki; SERBP1; - GenomeRNAi; 26135; - PRO; PR:Q8NC51; - Proteomes; UP000005640; Chromosome 1 Bgee; ENSG00000142864; Expressed in 236 organ(s), highest expression level in testis ExpressionAtlas; Q8NC51; baseline and differential Genevisible; Q8NC51; HS GO; GO:0005737; C:cytoplasm; IDA:UniProtKB GO; GO:0005829; C:cytosol; IDA:HPA GO; GO:0070062; C:extracellular exosome; HDA:UniProtKB GO; GO:0016020; C:membrane; HDA:UniProtKB GO; GO:0005634; C:nucleus; IDA:UniProtKB GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell GO; GO:0005886; C:plasma membrane; IEA:Ensembl GO; GO:0045296; F:cadherin binding; HDA:BHF-UCL GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:HGNC GO; GO:0003723; F:RNA binding; HDA:UniProtKB GO; GO:0032183; F:SUMO binding; IDA:UniProtKB GO; GO:0030578; P:PML body organization; IDA:UniProtKB GO; GO:0042981; P:regulation of apoptotic process; IEA:Ensembl GO; GO:0043488; P:regulation of mRNA stability; NAS:HGNC InterPro; IPR039764; HABP4/SERBP1 InterPro; IPR006861; HABP4_PAIRBP1-bd InterPro; IPR032381; IHABP4_N InterPro; IPR027205; SERBP1 PANTHER; PTHR12299; PTHR12299; 1 PANTHER; PTHR12299:SF29; PTHR12299:SF29; 1 Pfam; PF04774; HABP4_PAI-RBP1; 1 Pfam; PF16174; IHABP4_N; 1 SMART; SM01233; HABP4_PAI-RBP1; 1 1: Evidence at protein level; 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Isopeptide bond; Methylation; Nucleus; Phosphoprotein; Reference proteome; RNA-binding; Ubl conjugation INIT_MET 1 1 Removed. {ECO:0000244|PubMed:25944712, ECO:0000269|Ref.8} CHAIN 2 408 Plasminogen activator inhibitor 1 RNA- binding protein /FTId=PRO_0000058182 MOD_RES 25 25 Phosphoserine MOD_RES 52 52 N6-acetyllysine; alternate {ECO:0000250|UniProtKB:Q9CY58} MOD_RES 68 68 N6-acetyllysine MOD_RES 122 122 N6-acetyllysine MOD_RES 140 140 N6-acetyllysine MOD_RES 165 165 Omega-N-methylarginine {ECO:0000250|UniProtKB:Q9CY58} MOD_RES 188 188 Omega-N-methylarginine {ECO:0000250|UniProtKB:Q9CY58} MOD_RES 197 197 Phosphoserine {ECO:0000250|UniProtKB:Q6AXS5} MOD_RES 203 203 Phosphoserine MOD_RES 205 205 Phosphoserine MOD_RES 208 208 Phosphoserine MOD_RES 211 211 N6-acetyllysine; alternate MOD_RES 216 216 Omega-N-methylarginine MOD_RES 221 221 Phosphoserine MOD_RES 234 234 Phosphoserine MOD_RES 329 329 N6-acetyllysine {ECO:0000250|UniProtKB:Q9CY58} MOD_RES 330 330 Phosphoserine MOD_RES 364 364 Omega-N-methylarginine MOD_RES 367 367 Omega-N-methylarginine MOD_RES 370 370 Omega-N-methylarginine MOD_RES 392 392 Phosphoserine MOD_RES 394 394 Phosphoserine CROSSLNK 52 52 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate. CROSSLNK 102 102 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate. CROSSLNK 102 102 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate. CROSSLNK 211 211 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate. CROSSLNK 228 228 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate. CROSSLNK 228 228 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate. CROSSLNK 281 281 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate. CROSSLNK 281 281 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate. VAR_SEQ 203 208 Missing (in isoform 2 and isoform 4) {ECO:0000303|PubMed:11230166, ECO:0000303|PubMed:15489334, ECO:0000303|Ref.4} /FTId=VSP_011630 VAR_SEQ 233 247 Missing (in isoform 3 and isoform 4) {ECO:0000303|PubMed:10810093, ECO:0000303|PubMed:11230166, ECO:0000303|PubMed:15489334, ECO:0000303|Ref.4, ECO:0000303|Ref.9} /FTId=VSP_011631 MUTAGEN 102 102 K->R: Not sumoylated; when associated with R-228 and R-281 MUTAGEN 228 228 K->R: Not sumoylated; when associated with R-102 and R-281 MUTAGEN 281 281 K->R: Not sumoylated; when associated with R-102 and R-228 CONFLICT 55 55 A -> T (in Ref. 1; AAD34050) CONFLICT 101 101 L -> F (in Ref. 1; AAD34050) CONFLICT 312 312 N -> S (in Ref. 3; BAC11324) CONFLICT 376 376 R -> C (in Ref. 6; AAH02488) SEQUENCE 408 AA; 44965 MW; 2289992374FA6A96 CRC64; MPGHLQEGFG CVVTNRFDQL FDDESDPFEV LKAAENKKKE AGGGGVGGPG AKSAAQAAAQ TNSNAAGKQL RKESQKDRKN PLPPSVGVVD KKEETQPPVA LKKEGIRRVG RRPDQQLQGE GKIIDRRPER RPPRERRFEK PLEEKGEGGE FSVDRPIIDR PIRGRGGLGR GRGGRGRGMG RGDGFDSRGK REFDRHSGSD RSSFSHYSGL KHEDKRGGSG SHNWGTVKDE LTESPKYIQK QISYNYSDLD QSNVTEETPE GEEHHPVADT ENKENEVEEV KEEGPKEMTL DEWKAIQNKD RAKVEFNIRK PNEGADGQWK KGFVLHKSKS EEAHAEDSVM DHHFRKPAND ITSQLEINFG DLGRPGRGGR GGRGGRGRGG RPNRGSRTDK SSASAPDVDD PEAFPALA
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.


Lai C.-H.,et al.Genome Res. 10:703-713(2000).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 99.00
Cat# BP20793c
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Terms & Conditions