|Other Names||U6 snRNA-associated Sm-like protein LSm2, Protein G7b, Small nuclear ribonuclear protein D homolog, snRNP core Sm-like protein Sm-x5, LSM2, C6orf28, G7B|
|Target/Specificity||The synthetic peptide sequence is selected from aa 75-89 of HUMAN LSM2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320).|
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Provided below are standard protocols that you may find useful for product applications.
Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing.
Achsel T.,et al.EMBO J. 18:5789-5802(1999).
Olavesen M.G.,et al.Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
Schmarda A.,et al.Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Xie T.,et al.Genome Res. 13:2621-2636(2003).
Shiina S.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
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