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MOS Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P00540
Other Accession NP_005363
Clone Names 70920124
Additional Information
Gene ID 4342
Other Names Proto-oncogene serine/threonine-protein kinase mos, Oocyte maturation factor mos, Proto-oncogene c-Mos, MOS
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8069b was selected from the C-term region of human MOS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MOS
Tissue Location Expressed specifically in testis during spermatogenesis
Research Areas
Citations (0)

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Mos, the c-mos protooncogene product, is a key regulator of meiosis in vertebrates. MOS is a 39kDa proto oncogene (c-Mos) encoded protein serine/threonine kinase. MOS is a monomeric protein that indirectly activates MAP kinase (Erk1/2) by directly phosphorylating MAP kinase kinase (Mck, MAPKK, MKK). MOS is known as a cytostatic factor (CSF) and is also thought to arrest unfertilized amphibian and mammalian cells during M phase, thus regulating oocyte maturation. MOS is destroyed before fertilisation, after exit from meiosis II, making it a good marker for studies of eggs during oogenesis and maturation.


Caubet, J.F., et al., EMBO J. 4(9):2245-2248 (1985).Watson, R., et al., Proc. Natl. Acad. Sci. U.S.A. 79(13):4078-4082 (1982).Singh, B., et al., Prog Cell Cycle Res 3, 251-259 (1997).

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$ 80.00
Cat# BP8069b
Availability: In Stock
Bulk Size
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