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Natriuretic Peptide Receptor A Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P16066
Clone Names 3031007
Peptide ID 3031007
Additional Information
Gene ID 4881
Other Names Atrial natriuretic peptide receptor 1, Atrial natriuretic peptide receptor type A, ANP-A, ANPR-A, NPR-A, Guanylate cyclase A, GC-A, NPR1, ANPRA
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8111a was selected from the N-term region of human ANPA . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NPR1
Synonyms ANPRA
Function Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations ( 0 )


ANPA is a receptor for atrial natriuretic peptide. It exhibits guanylate cyclase activity on binding of ANF. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction. This Type I membrane protein belongs to the adenylyl cyclase class-4/guanylyl cyclase family and contains 1 protein kinase-like domain.


Takahashi, Y., et al., Biochem. Biophys. Res. Commun. 246(3):736-739 (1998).Pardhasaradhi, K., et al., Cell. Mol. Neurobiol. 14(1):1-7 (1994).Lowe, D.G., et al., EMBO J. 8(5):1377-1384 (1989).

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$ 99.00
Cat# BP8111a
Availability: In Stock
Bulk Size
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