|Other Names||Killer cell immunoglobulin-like receptor 2DS1, CD158 antigen-like family member H, MHC class I NK cell receptor Eb6 ActI, CD158h, KIR2DS1, CD158H|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8900a was selected from the N-term region of human KIR2DS1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor on natural killer (NK) cells for some HLA-C alleles such as w6. Does not inhibit the activity of NK cells.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein; Extracellular side|
|Tissue Location||Expressed by NK cells.|
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Provided below are standard protocols that you may find useful for product applications.
KIR2DS1 is the receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
Uhrberg M., et.al., Immunity 7:753-763(1997).Biassoni R., et.al., J. Exp. Med. 183:645-650(1996).
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