|Other Names||Atlastin-2, 365-, ADP-ribosylation factor-like protein 6-interacting protein 2, ARL-6-interacting protein 2, Aip-2, ATL2, ARL6IP2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (PubMed:18270207, PubMed:19665976, PubMed:27619977).|
|Cellular Location||Endoplasmic reticulum membrane; Multi- pass membrane protein Note=Localizes at endoplasmic reticulum (ER) three-way tubular junctions (PubMed:27619977).|
|Tissue Location||Expressed in peripheral tissues (at protein level).|
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ATLA2 is GTPase tethering membranes through formation of trans-homooligomer and mediating homotypic fusion of endoplasmic reticulum membranes. This protein play a role in endoplasmic reticulum tubular network biogenesis.
Hu,J. Cell 138 (3), 549-561 (2009)Rismanchi,N. Hum. Mol. Genet. 17 (11), 1591-1604 (2008)Abel,A. Neurogenetics 5 (4), 239-243 (2004)
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