|Other Names||Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, TCF-14, Transcription factor HNF-4, HNF4A, HNF4, NR2A1, TCF14|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||HNF4, NR2A1, TCF14|
|Function||Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1- antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- alpha. May be essential for development of the liver, kidney and intestine.|
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Provided below are standard protocols that you may find useful for product applications.
HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines.
Koh, W., et al. BMC Genomics 11 SUPPL 1, S6 (2010) Wang, F., et al. Chin. Med. J. 122(20):2477-2482(2009)Taghavi, S.M., et al. Cardiovasc Diabetol 8, 63 (2009) Guo, H., et al. Biochem. J. 394 (PT 2), 379-387 (2006) Hong, Y.H., et al. J. Biol. Chem. 278(30):27495-27501(2003)
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