|Other Names||Cytokine receptor common subunit gamma, Interleukin-2 receptor subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, gammaC, p64, CD132, IL2RG|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cell surface|
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Provided below are standard protocols that you may find useful for product applications.
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain.
Ross, J.A., et al. J. Biol. Chem. 285(6):3582-3591(2010)Ameratunga, R., et al. N. Z. Med. J. 122(1304):46-53(2009)Clark, P.A., et al. Hum. Genet. 96(4):427-432(1995)Ohbo, K., et al. J. Biol. Chem. 270(13):7479-7486(1995)Bamborough, P., et al. Structure 2(9):839-851(1994)
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