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RAB3IP Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96QF0
Peptide ID 91102056
Additional Information
Gene ID 117177
Other Names Rab-3A-interacting protein, Rab3A-interacting protein, Rabin-3, SSX2-interacting protein, RAB3IP {ECO:0000312|EMBL:CAC598361}, RABIN8
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB3IP {ECO:0000312|EMBL:CAC59836.1}
Synonyms RABIN8
Function Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
Cellular Location Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Note=Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus Activation of protein kinase C results in redistribution to the periphery of lamellipodia. In the cytoskeleton, localizes to cortical actin
Tissue Location Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or liver
Research Areas
Citations (0)

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The specific function of this protein remains unknown. It belongs to the SEC2 family and may be involved in protein transport. It is predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus. There are 8 isoforms produced by alternative splicing.


??enkatesan, K., et al. Nat. Methods 6(1):83-90(2009)??attula, K., et al. Mol. Biol. Cell 13(9):3268-3280(2002)??e Bruijn, D.R., et al. Genes Chromosomes Cancer 34(3):285-298(2002)??ischer, U., et al. Int. J. Oncol. 20(1):173-176(2002)??rondyk, W.H., et al. Mol. Cell. Biol. 15(3):1137-1143(1995)

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$ 99.00
Cat# BP9545c
Availability: In Stock
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