RAIDD Blocking Peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P78560 |
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Other Accession | AAH37905 |
Gene ID | 8738 |
Calculated MW | 22745 Da |
Gene ID | 8738 |
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Application & Usage | The peptide is used for blocking the antibody activity of RAIDD. Incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C usually completely blocks the antibody activity in Western blotting. |
Other Names | Death domain-containing protein CRADD, Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD, RAIDD |
Target/Specificity | RAIDD |
Formulation | 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | RAIDD Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CRADD |
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Synonyms | RAIDD |
Function | Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. |
Cellular Location | Cytoplasm. Nucleus |
Tissue Location | Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney |
Research Areas
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$ 95.00
Cat# PBV10017b-50
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