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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   TROY/TAJ Blocking Peptide   

TROY/TAJ Blocking Peptide

Product Information
Primary Accession Q9JLL3
Gene ID 29820
Additional Information
Application & Usage The peptide is used for blocking the antibody activity of Troy/TAJ. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Tumor necrosis factor receptor superfamily member 19, TRADE, Toxicity and JNK inducer, Tnfrsf19, Taj, Troy
Target/Specificity TROY/TAJ
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsTROY/TAJ Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tnfrsf19
Synonyms Taj, Troy
Function Can mediate activation of c-Jun and NF-kappa-B. May promote caspase-independent cell death (By similarity). Isoform 2 and isoform 3 may act as decoy receptors.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 4: Cell membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in adult brain, and in embryos from day 11-17, but not earlier. Detected in embryonic brain and epithelium, and at lower levels in adult heart, lung and liver. In neonatal mice, mainly in hair follicles and neuron-like cells in the cerebellum, but not in the skin epidermis. Isoform 3 was found in embryonic day 17.5 skin but not in brain and liver EMBL; AF173166; AAF19795.1; -; mRNA EMBL; AF167552; AAF71825.1; -; mRNA EMBL; AF167554; AAF71827.1; -; mRNA EMBL; AF167553; AAF71826.1; -; mRNA EMBL; AB040432; BAB03267.1; -; mRNA EMBL; AB040433; BAB03268.1; -; mRNA EMBL; AF247000; AAK28397.1; -; mRNA EMBL; AK028146; BAC25774.1; -; mRNA EMBL; BC030062; AAH30062.1; -; mRNA CCDS; CCDS36941.1; -. [Q9JLL3-1] RefSeq; NP_001157627.1; NM_001164155.1. [Q9JLL3-1] RefSeq; NP_038897.4; NM_013869.5. [Q9JLL3-1] UniGene; Mm.281356; - ProteinModelPortal; Q9JLL3; - SMR; Q9JLL3; - BioGrid; 205900; 1 CORUM; Q9JLL3; - STRING; 10090.ENSMUSP00000106865; - PhosphoSitePlus; Q9JLL3; - PaxDb; Q9JLL3; - PRIDE; Q9JLL3; - Ensembl; ENSMUST00000111234; ENSMUSP00000106865; ENSMUSG00000060548. [Q9JLL3-1] Ensembl; ENSMUST00000111236; ENSMUSP00000106867; ENSMUSG00000060548. [Q9JLL3-1] Ensembl; ENSMUST00000224371; ENSMUSP00000153577; ENSMUSG00000060548. [Q9JLL3-3] Ensembl; ENSMUST00000225730; ENSMUSP00000152920; ENSMUSG00000060548. [Q9JLL3-3] GeneID; 29820; - KEGG; mmu:29820; - UCSC; uc007ufi.2; mouse. [Q9JLL3-1] UCSC; uc007ufl.2; mouse. [Q9JLL3-3] UCSC; uc007ufn.2; mouse. [Q9JLL3-2] CTD; 55504; - MGI; MGI:1352474; Tnfrsf19 eggNOG; ENOG410IFRK; Eukaryota eggNOG; ENOG410ZU96; LUCA GeneTree; ENSGT00730000110978; - HOVERGEN; HBG069143; - InParanoid; Q9JLL3; - KO; K05155; - OMA; AWPLMQN; - OrthoDB; EOG091G0ADI; - TreeFam; TF331385; - PRO; PR:Q9JLL3; - Proteomes; UP000000589; Chromosome 14 Bgee; ENSMUSG00000060548; - Genevisible; Q9JLL3; MM GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO; GO:0005886; C:plasma membrane; IBA:GO_Central GO; GO:0001942; P:hair follicle development; IGI:MGI GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:MGI GO; GO:0046330; P:positive regulation of JNK cascade; IBA:GO_Central CDD; cd13418; TNFRSF19; 1 InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg InterPro; IPR022342; TNFR_19 InterPro; IPR034047; TNFRSF19_N PANTHER; PTHR12120:SF1; PTHR12120:SF1; 1 Pfam; PF00020; TNFR_c6; 1 PRINTS; PR01969; TNFACTORR19 SMART; SM00208; TNFR; 2 PROSITE; PS00652; TNFR_NGFR_1; 2 PROSITE; PS50050; TNFR_NGFR_2; 1 2: Evidence at transcript level; Alternative splicing; Cell membrane; Complete proteome; Disulfide bond; Glycoprotein; Membrane; Receptor; Reference proteome; Repeat; Secreted; Signal; Transmembrane; Transmembrane helix SIGNAL 1 29 CHAIN 30 416 Tumor necrosis factor receptor superfamily member 19 /FTId=PRO_0000034598 TOPO_DOM 30 170 Extracellular. TRANSMEM 171 191 Helical. TOPO_DOM 192 416 Cytoplasmic. REPEAT 33 72 TNFR-Cys 1 REPEAT 74 114 TNFR-Cys 2 REPEAT 116 149 TNFR-Cys 3; truncated CARBOHYD 105 105 N-linked (GlcNAc...) asparagine DISULFID 34 46 {ECO:0000255|PROSITE-ProRule:PRU00206} DISULFID 49 62 {ECO:0000255|PROSITE-ProRule:PRU00206} DISULFID 52 72 {ECO:0000255|PROSITE-ProRule:PRU00206} DISULFID 75 89 {ECO:0000255|PROSITE-ProRule:PRU00206} DISULFID 92 106 {ECO:0000255|PROSITE-ProRule:PRU00206} DISULFID 95 114 {ECO:0000255|PROSITE-ProRule:PRU00206} DISULFID 117 135 {ECO:0000255|PROSITE-ProRule:PRU00206} DISULFID 138 149 {ECO:0000255|PROSITE-ProRule:PRU00206} VAR_SEQ 150 150 T -> E (in isoform 2) /FTId=VSP_006513 VAR_SEQ 151 416 Missing (in isoform 2) /FTId=VSP_006514 VAR_SEQ 204 214 WSLRSQDIQYN -> CKLPSLCLTVK (in isoform 3). /FTId=VSP_006515 VAR_SEQ 215 416 Missing (in isoform 3) /FTId=VSP_006516 VAR_SEQ 340 348 NESAASLDS -> MLCFRFRDL (in isoform 4) /FTId=VSP_006517 VAR_SEQ 349 416 Missing (in isoform 4) /FTId=VSP_006518 CONFLICT 31 31 T -> A (in Ref. 1; AAF19795) CONFLICT 208 208 S -> P (in Ref. 1; AAF19795) CONFLICT 287 287 D -> N (in Ref. 1; AAF19795 and 2; AAF71825). CONFLICT 343 343 A -> T (in Ref. 2; AAF71825) SEQUENCE 416 AA; 45265 MW; 9BDC7C7A2D6A9C47 CRC64; MALKVLPLHR TVLFAAILFL LHLACKVSCE TGDCRQQEFK DRSGNCVLCK QCGPGMELSK ECGFGYGEDA QCVPCRPHRF KEDWGFQKCK PCADCALVNR FQRANCSHTS DAVCGDCLPG FYRKTKLVGF QDMECVPCGD PPPPYEPHCT SKVNLVKISS TVSSPRDTAL AAVICSALAT VLLALLILCV IYCKRQFMEK KPSWSLRSQD IQYNGSELSC FDQPRLRHCA HRACCQYHRD SAPMYGPVHL IPSLCCEEAR SSARAVLGCG LRSPTTLQER NPASVGDTMP AFFGSVSRSI CAEFSDAWPL MQNPLGGDSS LCDSYPELTG EDTNSLNPEN ESAASLDSSG GQDLAGTAAL ESSGNVSEST DSPRHGDTGT VWEQTLAQDA QRTPSQGGWE DRENLNLAMP TAFQDA
Research Areas
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$ 95.00
Cat# PBV10234b-50
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