Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   ECM Blocking Peptide   

ECM Blocking Peptide

Product Information
Primary Accession Q61508
Other Accession AAD13396
Gene ID 13601
Additional Information
Application & Usage The peptide is used for blocking the antibody activity of ECM. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Extracellular matrix protein 1, Secretory component p85, Ecm1
Target/Specificity ECM
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsECM Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ecm1
Function Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity (By similarity).
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Expressed in the connective tissues surronding developing long bones, but not in the cartilage. The long isoform is expressed in a number of tissues including liver, heart and lungs. The short isoform is expressed in skin and cartilage- containing tissues such as tail and front paw. No expression is found in brain. EMBL; L33416; AAA37535.1; -; mRNA EMBL; AK153009; BAE31648.1; -; mRNA EMBL; AK153471; BAE32022.1; -; mRNA CCDS; CCDS17619.1; -. [Q61508-1] RefSeq; NP_031925.2; NM_007899.2. [Q61508-1] UniGene; Mm.3433; - ProteinModelPortal; Q61508; - IntAct; Q61508; 1 STRING; 10090.ENSMUSP00000112665; - iPTMnet; Q61508; - PhosphoSitePlus; Q61508; - SwissPalm; Q61508; - UniCarbKB; Q61508; - PaxDb; Q61508; - PeptideAtlas; Q61508; - PRIDE; Q61508; - Ensembl; ENSMUST00000117507; ENSMUSP00000112665; ENSMUSG00000028108. [Q61508-1] GeneID; 13601; - KEGG; mmu:13601; - UCSC; uc008qko.2; mouse. [Q61508-1] CTD; 1893; - MGI; MGI:103060; Ecm1 eggNOG; ENOG410IVN8; Eukaryota eggNOG; ENOG4111TGN; LUCA GeneTree; ENSGT00390000006215; - HOGENOM; HOG000112317; - HOVERGEN; HBG005561; - InParanoid; Q61508; - OMA; CCHYPPS; - OrthoDB; EOG091G0NAE; - PhylomeDB; Q61508; - TreeFam; TF330786; - Reactome; R-MMU-114608; Platelet degranulation PRO; PR:Q61508; - Proteomes; UP000000589; Chromosome 3 Bgee; ENSMUSG00000028108; - CleanEx; MM_ECM1; - ExpressionAtlas; Q61508; baseline and differential Genevisible; Q61508; MM GO; GO:0031012; C:extracellular matrix; ISO:MGI GO; GO:0005615; C:extracellular space; IDA:MGI GO; GO:0019899; F:enzyme binding; ISO:MGI GO; GO:0005134; F:interleukin-2 receptor binding; IPI:MGI GO; GO:0043236; F:laminin binding; ISO:MGI GO; GO:0002020; F:protease binding; ISO:MGI GO; GO:0008022; F:protein C-terminus binding; ISO:MGI GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW GO; GO:0006954; P:inflammatory response; IMP:MGI GO; GO:0030502; P:negative regulation of bone mineralization; ISS:UniProtKB GO; GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IDA:MGI GO; GO:0010466; P:negative regulation of peptidase activity; ISS:UniProtKB GO; GO:0001503; P:ossification; IEA:UniProtKB-KW GO; GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB GO; GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB GO; GO:2000404; P:regulation of T cell migration; IMP:MGI GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IMP:MGI GO; GO:0002828; P:regulation of type 2 immune response; IMP:MGI GO; GO:0007165; P:signal transduction; IEA:InterPro InterPro; IPR008605; ECM1 InterPro; IPR020858; Serum_albumin-like PANTHER; PTHR16776; PTHR16776; 1 Pfam; PF05782; ECM1; 1 SUPFAM; SSF48552; SSF48552; 2 1: Evidence at protein level; Alternative splicing; Angiogenesis; Biomineralization; Complete proteome; Direct protein sequencing; Extracellular matrix; Glycoprotein; Mineral balance; Osteogenesis; Phosphoprotein; Reference proteome; Repeat; Secreted; Signal SIGNAL 1 19 CHAIN 20 559 Extracellular matrix protein 1 /FTId=PRO_0000021147 REPEAT 170 298 1 REPEAT 302 424 2 REGION 170 424 2 X approximate repeats MOD_RES 556 556 Phosphoserine {ECO:0000250|UniProtKB:Q62894} CARBOHYD 373 373 N-linked (GlcNAc...) asparagine CARBOHYD 463 463 N-linked (GlcNAc...) (high mannose) asparagine CARBOHYD 535 535 N-linked (GlcNAc...) (high mannose) asparagine VAR_SEQ 256 380 Missing (in isoform Short) /FTId=VSP_004230 CONFLICT 53 53 P -> L (in Ref. 1; AAA37535) CONFLICT 241 241 R -> P (in Ref. 1; AAA37535) CONFLICT 466 466 I -> V (in Ref. 1; AAA37535) SEQUENCE 559 AA; 62832 MW; F5282E5D7B78E696 CRC64; MGTVSRAALI LACLALASAA SEGAFKASDQ REMTPERLFQ HLHEVGYAAP PSPPQTRRLR VDHSVTSLHD PPLFEEQREV QPPSSPEDIP VYEEDWPTFL NPNVDKAGPA VPQEAIPLQK EQPPPQVHIE QKEIDPPAQP QEEIVQKEVK PHTLAGQLPP EPRTWNPARH CQQGRRGVWG HRLDGFPPGR PSPDNLKQIC LPERQHVIYG PWNLPQTGYS HLSRQGETLN VLETGYSRCC RCRSDTNRLD CLKLVWEDAM TQFCEAEFSV KTRPHLCCRL RGEERFSCFQ KEAPRPDYLL RPCPVHQNGM SSGPQLPFPP GLPTPDNVKN ICLLRRFRAV PRNLPATDAI QRQLQALTRL ETEFQRCCRQ GHNHTCTWKA WEGTLDGYCE RELAIKTHPH SCCHYPPSPA RDECFAHLAP YPNYDRDILT LDLSRVTPNL MGQLCGSGRV LSKHKQIPGL IQNMTIRCCE LPYPEQACCG EEEKLAFIEN LCGPRRNSWK DPALCCDLSP EDKQINCFNT NYLRNVALVA GDTGNATGLG EQGPTRGTDA NPAPGSKEE
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 95.00
Cat# PBV10388b-50
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Other Products

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Terms & Conditions