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- BACKGROUND
| Primary Accession | Q8WTS1 |
|---|---|
| Other Accession | AAD34053 |
| Gene ID | 51099 |
| Calculated MW | 39096 Da |
| Gene ID | 51099 |
|---|---|
| Application & Usage | The peptide is used for blocking the antibody activity of CGI-58. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C. |
| Other Names | 1-acylglycerol-3-phosphate O-acyltransferase ABHD5, 2.3.1.51, Abhydrolase domain-containing protein 5, Lipid droplet-binding protein CGI-58, ABHD5, NCIE2 |
| Target/Specificity | CGI-58 |
| Formulation | 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | CGI-58 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ABHD5 |
|---|---|
| Synonyms | NCIE2 |
| Function | Lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis (PubMed:18606822). May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2 (PubMed:16679289). Involved in keratinocyte differentiation (PubMed:18832586). Regulates lipid droplet fusion (By similarity). |
| Cellular Location | Cytoplasm. Lipid droplet. Note=Colocalized with PLIN and ADRP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA (By similarity). |
| Tissue Location | Widely expressed in various tissues, including lymphocytes, liver, skeletal muscle and brain. Expressed by upper epidermal layers and dermal fibroblasts in skin, hepatocytes and neurons (at protein level). |
Research Areas
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$ 95.00
Cat# PBV10426b-50
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